International research collaboration uses FDA-approved drugs to slow aging in nematodes


An international research collaboration that includes the University of Arkansas for Medical Sciences (UAMS) has discovered that aging in nematodes (worms) can be slowed and even reversed by a number of Food and Drug Administration (FDA)-approved drugs, findings that have the potential to extend human lifespan.

The study findings are published in Scientific Reports.

The collaboration was led by Robert J.S. Reis, D.Phil., at UAMS, and Peter Fedichev, Ph.D., a founder of the longevity biotech startup Gero. Other collaborators are from the Skolkovo Institute of Science and Technology (SIST) and Moscow Institute of Physics and Technology (MIPT).

The research team identified 10 FDA-approved drug compounds that slowed the aging process in nematodes.

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